In World War II London, nine-year-old George is evacuated to the countryside by his mother, Rita, to escape the bombings. Defiant and determined to return to his family, George embarks on an epic, perilous journey back home as Rita searches for him.

Paddington travels to Peru to visit his beloved Aunt Lucy, who now resides at the Home for Retired Bears. With the Brown Family in tow, a thrilling adventure ensues when a mystery plunges them into an unexpected journey through the Amazon rainforest and up to the mountain peaks of Peru.

Two young missionaries are forced to prove their faith when they knock on the wrong door and are greeted by a diabolical Mr. Reed, becoming ensnared in his deadly game of cat-and-mouse.